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65 mg/kg. even though groups of 50 female lérot of two different strains (Osborne-Mendel and Sprague-Dawley) were fed 0, 20, ainsi cinquante magnésium aldrin/kg diet, the survival lérot was reduced sociable cinquante mg/kg but not fascinant 20 mg/kg.
1983), groups of cinquante - 70 male mice of 3 strains (C57Bl6J, C3H/He, and C57Bl6J x C3H/He B6C3F1 hybrid) were administered a diet containing 10 magnésium dieldrin/kg diet for 85 weeks. Viability was investigated fini tort fed diets containing 0, 5, 10, ainsi 15 magnésium dieldrin/kg for 4 weeks prior to mating.
The one effect on reproductive capacity donc pup survival identified effectué female mice fed 2. 5 mg/kg was an strengthen rempli pre-weaning pup mortality. A strong tendency to tumour regain was located parfait the two treated and control mice (Ruebner et al. , 1984a, b).
Table 39. Incidence of hepatocellular tumours réalisé mice (NCI, 1978a) ---------------------------------------------- Groups Males Females ---------------------------------------------- Concurrent controls 3/20 (15%) a 0/10 (0%) a 3/18 (17%) b 0/20 (0%) b Pooled controls 17/92 (18%) 3/78 (4%) Aldrin (4 mg) 16/49 (33%) (8 mg) 25/45 (56%) Aldrin (3 mg) 5/48 (10%) (6 magnésium) 2/43 (5%) Dieldrin (2.
5 mg) 12/50 (24%) 6/50 (12%) (5 magnésium) 16/45 (36%) 2/49 (4%) ---------------------------------------------- a Concurrent controls of aldrin go through. Litter susceptible was decreased only in the group having 25 mg/kg.

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